AI-Edigene® BRAF p.V600M Reference Standard Plus询价

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产品数据库

CBP10425
Format Genomic DNA
Description BRAF, serine/threonine-protein kinase B-raf, is a member of the Raf family of serine/threonine protein kinases, which signals through the MAP kinase pathway to regulate cell proliferation and cell growth (PMID: 24737949, PMID: 29540830). BRAF mutations have been identified in a variety of cancers, including, colorectal (PMID: 30122982), lung (PMID: 29729495), thyroid (PMID: 12970315), and melanoma (PMID: 24737949), and a number of mutations have also been demonstrated to confer drug resistance (PMID: 27478040).
Technical Data
DNA Change c.1798G>A
AA Change p.V600M
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000288602
Cosmic ID COSM1130
Chr position(GRCh37) chr7:140453137
Buffer Tris-EDTA
Product Information
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 4℃
Expiry 36 months from the date of manufacture


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