NRAS p.Q61R Reference StandardEnquiry

Product Description

Product database

CBP10309
Format Genomic DNA
Description NRAS Q61R is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). Q61R results in a loss of Nras GTPase function as indicated by increased GTP-bound Nras, which leads to activation of Mapk signaling in culture (PMID: 16818621).
Technical Data
DNA Change c.182A>G
AA Change p.Q61R
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000369535
Cosmic ID COSM584
Chr position(GRCh37) chr1:115256529
Buffer Tris-EDTA
Product Information
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 4℃
Expiry 36 months from the date of manufacture

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