KRAS p.G12R Reference StandardEnquiry

Product Description

Product database

CBP10295
Format Genomic DNA
Description KRAS G12R is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12R results in decreased Kras GTPase activity and increased activation of downstream signaling in cell culture (PMID: 23455880, PMID: 26037647).
Technical Data
DNA Change c.34G>C
AA Change p.G12R
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000311936
Cosmic ID COSM518
Chr position(GRCh37) chr12:25398285
Buffer Tris-EDTA
Product Information
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 4℃
Expiry 36 months from the date of manufacture

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Copyright ©2021 www.cobioer.com All Rights Reserved Nanjing Cobioer Gene Technology Co., Ltd. Su ICP No. 2021000293 Technical support: Tianrun Shunteng